Life Science Research Professional 2
Company: Stanford University
Location: Stanford
Posted on: November 12, 2024
Job Description:
The Bassik Lab at Stanford University
(http://bassiklab.stanford.edu) is seeking a Life Science Research
Professional 2 to be an integral member of a research team that is
developing novel genetic tools, including ultracomplex CRISPR/Cas9
libraries, to conduct genetic screens in a range of medically
relevant areas, such as cancer, neurodegeneration and infectious
disease. The goal of this work is to understand (1) the biology of
cancer development and identify novel therapeutic drug targets, as
well as to (2) understand how macrophage cells of the immune system
recognize and destroy pathogens ranging from protein aggregates to
tumor cells. Candidate must be willing to work in a research team,
be organized, enjoy problem solving, and have strong communication
skills. This is a fantastic opportunity for a motivated, creative,
and reliable person to participate in highly collaborative,
cutting-edge research at the forefront of modern biology, with real
world applications to develop new therapeutics to improve human
health.
Responsibilities include cell culture and maintenance of human cell
lines, basic molecular biology (PCR, cloning, running DNA and
protein gels), flow cytometry, preparation of samples for deep
sequencing, confocal microscopy, basic statistical calculations,
and other duties as assigned. The LSRP will be expected to work
closely with the PI to develop protocols, interpret and analyze the
results of experiments, and suggest modifications to procedures as
appropriate. The position includes lab management tasks such as
ordering supplies, maintaining lab records, and adhering to safety
regulations. The LSRP is expected to keep abreast of scientific
literature and contribute new ideas and techniques to the lab, as
well as attend lab meetings and journal clubs. There will be ample
opportunity and encouragement for independent scientific
development, project development, and paper writing for highly
motivated candidates.
Duties include:
Independently conduct a portion of
the research project(s). Make recommendations on experimental
design and/or research direction to principal
investigator.Independently conduct complex (lab and/or field)
experiments to gather data for a portion of a major research
project.Interpret and analyze results, often where few guidelines
exist, and make modifications to existing procedures and
protocols.Develop new research protocols where appropriate
protocols are not described in the literature or where modification
or adaptation of standard procedures and protocols is
required.Participate in multidisciplinary teams across different
faculties or schools.Perform ongoing literature review to remain
current with new procedures and related research; apply to ongoing
research and development of new protocols.Contribute substantively
to the preparation of papers for publication, especially in the
results section, and to publication of findings. Present ongoing
work to colleagues and/or academic conferences.Oversee supply and
equipment budget under supervision of principal investigator or
business manager.Work with health and safety department to ensure
lab complies with regulations and all required trainings.Supervise
(either formally or informally) staff or students as needed,
including oversight and direction on techniques, as well as
consultation on project work. Serve as a technical resource for
other research staff.Oversee the daily activities of the laboratory
including lab maintenance; maintain lab stock, manage chemical
inventory and safety records, and provide general lab support as
needed. May assist with purchasing laboratory equipment.*- Other
duties may also be assigned. DESIRED QUALIFICATIONS:
- Bachelor's degree in Biology, Bioengineering, Genetics,
Biochemistry, Molecular Biology, or related scientific field is
desired.
- Proficiency with basic molecular biology techniques, such as
gel electrophoresis, PCR, and recombinant DNA techniques
- Experience with mammalian tissue culture techniques
- Meticulous record keeping and organizational skills
- Experience with high throughput sequencing methods and sample
preparation, fluorescence microscopy, flow cytometry, lentivirus
handling, and computer programming.
- Experience with single-cell sequencing EDUCATION & EXPERIENCE
(REQUIRED): Bachelor's degree in related scientific field and two
years of relevant work experience; or Master's degree in a related
scientific field. KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master
computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to maintain detailed records of experiments and
outcomes.
- Ability to work under deadlines with general guidance is
essential.
- Excellent organizational skills and demonstrated ability to
accurately complete detailed work. PHYSICAL REQUIREMENTS*:
- Frequently stand, walk, twist, bend, stoop, squat, grasp
lightly, use fine manipulation, grasp forcefully, perform
desk-based computer tasks, use telephone, write by hand, lift,
carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders,
sort and file paperwork or parts.
- Rarely climb, scrub, and mix or operate hand and foot
controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder
level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous
environment.
- Position may require repetitive motion.*- Consistent with its
obligations under the law, the University will provide reasonable
accommodation to any employee with a disability who requires
accommodation to perform the essential functions of his or her job.
WORKING CONDITIONS:
- May require working in close proximity to blood borne
pathogens.
- Position may at times require the employee to work with or be
in areas where hazardous materials and/or infectious diseases are
present.
- Employee must perform tasks that require the use of personal
protective equipment, such as safety glasses and shoes, protective
clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research
requirements and business needs. WORK STANDARDS (from JDL):
- Interpersonal Skills: Demonstrates the ability to work well
with Stanford colleagues and clients and with external
organizations.
- Promote Culture of Safety: Demonstrates commitment to personal
responsibility and value for safety; communicates safety concerns;
uses and promotes safe behaviors bases on training and lessons
learned.
- Subject to and expected to comply with all applicable
University policies and procedures, including but not limited to
the personnel policies and other policies found in the University's
Administrative Guide, .
The expected pay range for this position is $71,000 to $88,000 per
annum. Stanford University provides pay ranges representing its
good faith estimate of what the university reasonably expects to
pay for a position. The pay offered to a selected candidate will be
determined based on factors such as (but not limited to) the scope
and responsibilities of the position, the qualifications of the
selected candidate, departmental budget availability, internal
equity, geographic location and external market pay for comparable
jobs.
At Stanford University, base pay represents only one aspect of the
comprehensive rewards package. The Cardinal at Work website ()
provides detailed information on Stanford's extensive range of
benefits and rewards offered to employees. Specifics about the
rewards package for this position may be discussed during the
hiring process.
The job duties listed are typical examples of work performed by
positions in this job classification and are not designed to
contain or be interpreted as a comprehensive inventory of all
duties, tasks, and responsibilities. Specific duties and
responsibilities may vary depending on department or program needs
without changing the general nature and scope of the job or level
of responsibility. Employees may also perform other duties as
assigned.
Consistent with its obligations under the law, the University will
provide reasonable accommodations to applicants and employees with
disabilities. Applicants requiring a reasonable accommodation for
any part of the application or hiring process should contact
Stanford University Human Resources at . For all other inquiries,
please submit a .
Stanford is an equal employment opportunity and affirmative action
employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, national origin, disability,
protected veteran status, or any other characteristic protected by
law.
Keywords: Stanford University, San Francisco , Life Science Research Professional 2, Other , Stanford, California
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