Life Science Research Professional 3
Company: Stanford University
Location: Stanford
Posted on: November 14, 2024
Job Description:
Stanford University is seeking a Life Science Research
Professional 3 to perform complex functions and activities involved
in defined research projects, and independently conduct a major
portion of the research project(s).You will be working with an
unparalleled leading-edge community of faculty and staff that are
fundamentally changing the world of health care. You will have the
opportunity to influence and drive change with your innovative
ideas, the ability to make a difference and participate in human
advancements. Our culture is fast-paced, energetic, and growing all
of the time. We offer a variety of benefits beyond traditional
medical, dental, retirement, and savings options:
Events and program for children,
sports camps, tuition optionsWorld-class intellectual stimulation
through learning and development classes, workshops, and onsite
conferences from leading-edge speakers and facultyWork/life and
family-friendly policies and reimbursementParticipation in
Stanford's social responsibility and sustainable programs for a
better worldA vibrant university culture that values the uniqueness
of each individualWe are seeking candidates who are progressive
thinkers, see challenges as simply problems to solve, and have the
spirit and energy to change the world.About the Department of
Pathology:The Department of Pathology at Stanford School of
Medicine, one of its founding departments, stands as a leader among
its peers nationwide. Our preeminent faculty spans from emerging
leaders to highly accomplished physicians and scientists, including
a Nobel laureate and members of the National Academy. Our mission
is to improve the diagnosis, treatment, and basic understanding of
the human disease. This is done through discovery (research),
education, and clinical care. Comprised of extraordinary faculty
and staff, our mission is to improve the ability to diagnose, treat
and understand the origin and manifestation of human disease, and
to care for those who have or are at risk to develop disease. We
accomplish this through our clinical services (in all fields of
anatomic and clinical pathology, including molecular and genomic
pathology, histocompatibility testing and transfusion medicine) and
research (which includes basic, translational and clinical research
into the origins and manifestations of disease, including efforts
to improve disease prediction and prevention as part of the goal of
achieving precision medicine and health), and also by educating
future leaders in pathology and related fields. Everything we do is
to achieve the goals of providing the highest quality of clinical
services to the patients for whom we passionately care, to advance
our ability to understand, diagnose, monitor and ultimately to cure
disease or to prevent or delay its occurrence, and to provide
outstanding education and career development opportunities to those
who share these goals.For more information about the department
visit Lab Overview: The Satpathy Lab studies fundamental principles
of the immune system in health, infection, and cancer (Parker et
al, Cell 2020; Flynn et al, Cell 2021). The lab particularly
focuses on single-cell genomic and multi-omic technologies (Yost et
al, Nature Medicine 2019; Rubin et al, Cell 2019) to study
immunological mechanisms of disease directly in samples isolated
from patients. For more information about our multidisciplinary
research laboratory, see We are recruiting a Life Science Research
Professional to join a new research group within the lab focused on
using gene editing and high-dimensional screening in primary human
immune cells to parse the biology of cancer-immune interactions and
develop new immune cell-based cancer therapies. This gene editing
focused group is located at the Stanford Blood Center (3373
Hillview Ave), a short bike ride from the main campus, and is led
by Dr. Theo Roth, MD, PhD. The group's work involves synthetic
re-writing of human T cell genomes using non-viral gene editing
(Roth et al, Nature 2018) in high throughput arrayed and pooled
genetic screens (Roth et al, Cell 2020; Blaeschke et al, Cell
2023).About the Position: Working as part of a multidisciplinary
group, the Life Science Research Professional 3 will lead the
design and construction of large libraries of DNA sequences for
cellular engineering experiments, isolate and culture primary human
immune cells and stem cells, and large scale pooled genetic
screens. Additional major responsibilities will include
next-generation sequencing library production and analysis. The
LRSP will assist in grant applications, reporting, and publication
of laboratory findings, as well as mentorship of technicians,
trainees, and students in the laboratory.Duties include:
Design research approaches for a
major portion of research project(s), including background
research, experimental design and execution, problem-solving, and
writing up for publication.Develop new protocols; test and evaluate
a variety of approaches.Perform complex (lab and/or field)
experiments and maintain detailed records of experiments and
outcomes; analyze and interpret research data resulting from
original procedures and methods.Assist with new research proposals
and applications for funding and grants.Lead or participate in
multidisciplinary teams across different faculties or
schools.Prepare periodic progress reports or written reports on all
phases of the research project.Contribute substantively to the
preparation of papers for publication, especially in the results
section. May be a co-author on publications. Present ongoing work
and findings to colleagues at academic conferences.Perform ongoing
literature review to remain current with new procedures and related
research; propose new research directions based on new advances
discussed in literature.Work with health and safety department to
ensure lab complies with regulations and all required
trainings.Formally supervise and train new staff or students as
needed, including hiring, performance management, and related
duties, in addition to instruction on techniques and consultation
on project work.* - Other duties may also be assigned Desired
Qualifications:
An MD (or equivalent), PhD, or BS
with 7+ years of experience in independent immunology, stem cell,
and/or gene editing research.Working with and publishing on gene
editing in eukaryotic cells.Experience with primary immune cell
and/or induced pluripotent stem cell culture.Practical and applied
background and expertise relevant to genetic perturbation
screening.Experience writing or reporting on research
grants.Analysis of biological data and preparation of
publications.Experience with molecular cloning procedures.Hands-on
experience operating NGS equipment.Education & Experience
(Required):
- Bachelor's degree in related scientific field and four years of
relevant work experience; or Master's degree in a related
scientific field and two years relevant experience; or PhD in
related science field.Knowledge, Skills and Abilities (Required):
Comprehensive understanding of
scientific principles.Expert level knowledge and skills in field of
science related to research project.General computer skills,
experience with databases and scientific applications, and ability
to quickly learn and master computer programs.Strong analytical
skills and excellent judgment.Ability to work under deadlines with
general guidance is essential.Excellent organizational skills and
demonstrated ability to complete detailed work
accurately.Developing project management skills.Physical
Requirements*:
Frequently stand, walk, twist, bend,
stoop, squat, grasp lightly, use fine manipulation, grasp
forcefully, perform desk-based computer tasks, use telephone, write
by hand, lift, carry, push and pull objects weighing over 50
pounds. Occasionally sit, kneel, crawl, reach and work above
shoulders, sort and file paperwork or parts.Rarely climb, scrub,
sweep, mop, chop and mix or operate hand and foot controls.Must
have correctible vision to perform duties of the job.Ability to
bend, squat, kneel, stand, reach above shoulder level, and move on
hard surfaces for up to eight hours.Ability to lift heavy objects
weighing up to 50 pounds.Ability to work in a dusty, dirty, and
odorous environment.Position may require repetitive motion.* -
Consistent with its obligations under the law, the University will
provide reasonable accommodation to any employee with a disability
who requires accommodation to perform the essential functions of
his or her job.Working Conditions:
May require working in close
proximity to blood borne pathogens.May require work in an
environment where animals are used for teaching and
research.Position may at times require the employee to work with or
be in areas where hazardous materials and/or infectious diseases
are present.Employee must perform tasks that require the use of
personal protective equipment, such as safety glasses and shoes,
protective clothing and gloves, and possibly a respirator.May
require extended or unusual work hours based on research
requirements and business needs.Due to the nature of the work, this
position will work fully on-site.The expected pay range for this
position is $93,062 to $111,670 per annum.Stanford University
provides pay ranges representing its good faith estimate of what
the university reasonably expects to pay for a position. The pay
offered to a selected candidate will be determined based on factors
such as (but not limited to) the scope and responsibilities of the
position, the qualifications of the selected candidate,
departmental budget availability, internal equity, geographic
location and external market pay for comparable jobs.At Stanford
University, base pay represents only one aspect of the
comprehensive rewards package. The Cardinal at Work website ()
provides detailed information on Stanford's extensive range of
benefits and rewards offered to employees. Specifics about the
rewards package for this position may be discussed during the
hiring process.Why Stanford is for You
Imagine a world without search engines or social platforms.
Consider lives saved through first-ever organ transplants and
research to cure illnesses. Stanford University has revolutionized
the way we live and enrich the world. Supporting this mission is
our diverse and dedicated 17,000 staff. We seek talent driven to
impact the future of our legacy. Our culture and unique perks
empower you with:
Freedom to grow. We offer career
development programs, tuition reimbursement, or course auditing.
Join a TedTalk, film screening, or listen to a renowned author or
global leader speak.A caring culture. We provide superb retirement
plans, generous time-off, and family care resources.A healthier
you. Climb our rock wall or choose from hundreds of health or
fitness classes at our world-class exercise facilities. We also
provide excellent health care benefits.Discovery and fun. Stroll
through historic sculptures, trails, and museums.Enviable
resources. Enjoy free commuter programs, ride-sharing incentives,
discounts and moreThe job duties listed are typical examples of
work performed by positions in this job classification and are not
designed to contain or be interpreted as a comprehensive inventory
of all duties, tasks, and responsibilities. Specific duties and
responsibilities may vary depending on department or program needs
without changing the general nature and scope of the job or level
of responsibility. Employees may also perform other duties as
assigned.Consistent with its obligations under the law, the
university will provide reasonable accommodation to any employee
with a disability who requires accommodation to perform the
essential functions of his or her job.Stanford is an equal
employment opportunity and affirmative action employer. All
qualified applicants will receive consideration for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, national origin, disability, protected veteran
status, or any other characteristic protected by law.
Keywords: Stanford University, San Francisco , Life Science Research Professional 3, Other , Stanford, California
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