Associate Principal Statistical Analyst

Company: Revolution Medicines
Location: San Francisco
Posted on: March 24, 2025

Job Description:

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.The Opportunity:The position requires 10-14 years of Statistical Programming experience with exploratory-stage oncology clinical trials, providing programming support and oversight of one or more clinical programs within Statistical Programming function. In addition to hands-on Programming, this position may require assisting in Programming infrastructure and process development, providing technical support and guidance during regulatory submissions while ensuring conformance to CDISC standards and submission guidelines. This person will be required to collaborate closely with cross-functional teams to help enhance process efficiency and quality of statistical outputs. The title may vary based on the candidate's experience.Specific responsibilities:

• Provide project teams with strategic input and technical expertise as it relates to Statistical Programming.
• Provide management and oversight of statistical programming contractors and CROs (e.g., SDTM vendors, independent statistical analysis center for DMCs).
• Ensure quality and timely delivery of analysis for our clinical trials.
• Ensure accuracy of clinical trial results for internal and external audiences (e.g., regulatory authorities, academic community, and healthcare providers) via biometrics QC of documents with clinical data.
• Ensure that the interpretation of data obtained from our clinical trials is accurate, scientifically sound and credible.
• Oversee the programming support for relevant deliverables, such as Investigator Brochures, publications, US and ex-US regulatory submissions, including CDISC compliant datasets (SDTM, ADaM) and data documentation, Reviewer's Guide, TLFs, Statistical Analysis Plans (study specific, ISS, ISE, Exposure-Response), blank and annotated CRFs, and actual patient CRFs.
• Hands-on programming of in-house deliverables including but not limited to Dose Committee meetings, Board of Director meetings, Exploratory Analysis, etc.
• Verification Review of documents, spreadsheets, slides for in-house presentations and external publications.
• Experience with design and development of macro utilities or any new applications and capabilities to help with process improvement and efficiency is highly desirable.Required Skills, Experience and Education:
• MS, BS/BA degree or other suitable qualification with relevance to the field.
• Hands-on experience of programming for early-stage clinical trials.
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy environment.
• Excellent written and verbal communication skills.
• Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute goals as a member of an interdisciplinary team is extremely important.
• Industry experience is essential.Preferred Skills:
• A demonstrable record of strong leadership and teamwork.
• Oncology experience is preferred.The base salary range for this full-time position is $158,000 to $198,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition and veteran status.
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Keywords: Revolution Medicines, San Francisco , Associate Principal Statistical Analyst, Professions , San Francisco, California